You are here: Home> South Korea>K-REACH>CAS 616-45-5> CAS 616-45-5 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: 2-Pyrrolidone (CAS 616-45-5) | Author: GESTIS Database on Hazardous Substances | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Hawley's Condensed Chemical Dictionary 12th. edition | Author: Lewis R.J. (Editor) | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Industrial Solvents Handbook 4th ed. | Author: Flick E.W. (ed.) | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 2-Pyrrolidone (CAS 616-45-5) | Author: GESTIS Database on Hazardous Substances | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Stoffwerte Pyrrolidon | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Stoffwerte Pyrrolidon | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdrücke von Pyrrolidon-2 und 15 N-substituierten Pyrrolidon-Derivaten im Bereich unter 5 mbar | Author: BASF AG | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdrücke von Pyrrolidon-2 und 15 N-substituierten Pyrrolidon-Derivaten im Bereich unter 5 mbar | Author: BASF AG | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Techniques of Chemistry 4th ed. Volume II. Organic Solvents | Author: Riddick J.A. Bunger W.B. Sakano T.K. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: 2-Pyrrolidone (CAS 616-45-5) | Author: GESTIS Database on Hazardous Substances | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: US EPA . Estimation Programs Interface Suite™ for Microsoft® Windows v 4.11. United States Environmental Protection Agency Washington DC USA; WSKOWWIN™ Version 1.42 | Author: U.S. Environmental Protection Agency 1200 Pennsylvania Ave. N.W. (Mail Code 7406M) Washington DC 20460 | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Bestimmung des Verteilungskoeffizienten POW von Pyrrolidon in n-Octanol/Wasser bei Raumtemperatur (25 °C) | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Bestimmung des Verteilungskoeffizienten POW von Pyrrolidon in n-Octanol/Wasser bei Raumtemperatur (25 °C) | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: EPI Suite (v4.1): KOWWIN v1.68 Programm | Author: Estimation Programs Interface Suite for Microsoft Windows v4.11 | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary skin irritation /corrosion study with HC1161 in the rabbit (4-hour semi-occlusive application) | Author: Notox B.V. | Year: 2003 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary skin irritation /corrosion study with HC1161 in the rabbit (4-hour semi-occlusive application) | Author: Notox B.V. | Year: 2003 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Gewerbetoxikologische Grundprüfung Pyrrolidon Roh. | Author: BASF AG | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Gewerbetoxikologische Grundprüfung Pyrrolidon Roh. | Author: BASF AG | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Results of the toxicological pretesting Pyrrolidone distilled | Author: BASF AG | Year: 1961 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Results of the toxicological pretesting Pyrrolidone distilled | Author: BASF AG | Year: 1961 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidon - Murine Local Lymph Node Assay (LLNA). | Author: BASF AG | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 2687-91-4 | EC 220-250-6 | 1-ethylpyrrolidin-2-one) |
- |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: N-Ethyl-2-pyrrolidon - Murine Local Lymph Node Assay (LLNA). | Author: BASF AG | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 2687-91-4 | EC 220-250-6 | 1-ethylpyrrolidin-2-one) |
- |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Test on 2-Pyrrolidone in the Ames- Salmonella/Microsome Reverse Mutation Assay | Author: Jagannath D.R.. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Test on 2-Pyrrolidone in the Ames- Salmonella/Microsome Reverse Mutation Assay | Author: Jagannath D.R.. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: 2-Pyrrolidone: Acute oral toxicity (Limit test) in the rat | Author: Safe Pharm Laboratories | Year: 1999 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: 2-Pyrrolidone: Acute oral toxicity (Limit test) in the rat | Author: Safe Pharm Laboratories | Year: 1999 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Results of the toxicological pretesting Pyrrolidone distilled | Author: BASF AG | Year: 1961 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Results of the toxicological pretesting Pyrrolidone distilled | Author: BASF AG | Year: 1961 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Bericht über die Prüfung von Pyrrolidon auf etwaige teratogene Wirkung an der Ratte bei peroraler Applikation. | Author: BASF AG | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Bericht über die Prüfung von Pyrrolidon auf etwaige teratogene Wirkung an der Ratte bei peroraler Applikation. | Author: BASF AG | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Gewerbetoxikologische Grundprüfung Pyrrolidon Roh. | Author: BASF AG | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Gewerbetoxikologische Grundprüfung Pyrrolidon Roh. | Author: BASF AG | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1953 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1953 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicity study on the zebra fish (Brachydanio rerio HAM. and BUCH.) | Author: BASF AG | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute toxicity study on the zebra fish (Brachydanio rerio HAM. and BUCH.) | Author: BASF AG | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Produktprüfung Fischtoxizitätstest | Author: BASF AG | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Produktprüfung Fischtoxizitätstest | Author: BASF AG | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Bestimmung der akuten Wirkung von Pyrrolidon dest. gegenüber dem Wasserfloh Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Bestimmung der akuten Wirkung von Pyrrolidon dest. gegenüber dem Wasserfloh Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: 2nd VCI ringtest 1976/77 | Author: BASF AG | Year: 1977 | Guideline: 301D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: 2nd VCI ringtest 1976/77 | Author: BASF AG | Year: 1977 | Guideline: 301D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Pyrrolidon dest.: Standtest | Author: BASF AG | Year: 1977 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Pyrrolidon dest.: Standtest | Author: BASF AG | Year: 1977 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals | Author: CITI | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Untitled | Author: BASF AG | Year: 1979 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Untitled | Author: BASF AG | Year: 1979 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: A Correlation Study of Biodegradability Determinations with Various Chemicals in Various Tests | Author: Gerike P and Fischer WK | Year: 1979 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methodenkombination zur sukzessiven Prüfung und Bewertung der biologischen Abbaubarkeit synthetischer Substanzen z.B. organischer Komplexbildner über allgemein gültige Summenparameter (BSB CO2 COD TOC). | Author: Fischer WK Gerike P and Schmid R | Year: 1974 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Untitled | Author: BASF AG | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Untitled | Author: BASF AG | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 872-50-4 | EC 212-828-1 | 1-methylpyrrolidin-2-one) |
- |