You are here: Home> South Korea>K-REACH>CAS 1185-55-3> CAS 1185-55-3 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial Reverse Mutation Assay with Trimethoxymethylsilane | Author: BioReliance | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bacterial Reverse Mutation Assay with Trimethoxymethylsilane | Author: BioReliance | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Methyltrimethoxysilane: Determination of the Freezing Point/Freezing Range | Author: Harlan Laboratories Ltd | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Methyltrimethoxysilane: Determination of the Freezing Point/Freezing Range | Author: Harlan Laboratories Ltd | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Methyltrimethoxysilane: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Flow-Through Test Conditions | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Methyltrimethoxysilane: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Flow-Through Test Conditions | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: CRC Handbook of Chemistry and Physics | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range Finding Tests on Methyl Trimethoxysilane | Author: Mellon Institute | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range Finding Tests on Methyl Trimethoxysilane | Author: Mellon Institute | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Methyltrimethoxysilane: Acute Toxicity to the Cladoceran, Daphnia magna, Under Flow-Through Test Conditions | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Methyltrimethoxysilane: Acute Toxicity to the Cladoceran, Daphnia magna, Under Flow-Through Test Conditions | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Final Report Determination of Physico-chemical Properties of SILAN M1-TRIMETHOXY (CAS No. 1185-55-3) | Author: Wacker Chemie AG | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Final Report Determination of Physico-chemical Properties of SILAN M1-TRIMETHOXY (CAS No. 1185-55-3) | Author: Wacker Chemie AG | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dynasylan PTMO - Determination of the biodegradability in the DOC DIE-AWAY test | Author: Hüls Corporation | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Dynasylan PTMO - Determination of the biodegradability in the DOC DIE-AWAY test | Author: Hüls Corporation | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of KOWWIN v1.67 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (Log Kow) of organosilicon compounds Version 3 | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of KOWWIN v1.67 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (Log Kow) of organosilicon compounds Version 3 | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions Version 3 | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions Version 3 | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial Reverse Mutation test with Methyltrimethoxysilane | Author: TNO | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bacterial Reverse Mutation test with Methyltrimethoxysilane | Author: TNO | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Methyltrimethoxysilane (29 223 R.P) et trimethoxysilane (29 241 R.P) toxicite orale chez la souris et tolerance locale oculaire chez le lapin | Author: Societe des Usines Chimiques Rhone-Poulenc | Year: 1972 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Methyltrimethoxysilane (29 223 R.P) et trimethoxysilane (29 241 R.P) toxicite orale chez la souris et tolerance locale oculaire chez le lapin | Author: Societe des Usines Chimiques Rhone-Poulenc | Year: 1972 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazelton Laboratories | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazelton Laboratories | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazelton Laboratories | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazelton Laboratories | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity evaluation of Dow Corning® Z-6070 (Methyltrimethoxysilane) in the Ames Bacterial Assay System | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity evaluation of Dow Corning® Z-6070 (Methyltrimethoxysilane) in the Ames Bacterial Assay System | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics, 88th Edition | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: CRC Handbook of Chemistry and Physics, 88th Edition | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Contact hypersensitivity in albino guinea pigs, Buehler test | Author: Toxikon | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Contact hypersensitivity in albino guinea pigs, Buehler test | Author: Toxikon | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Methyltrimethoxysilane Contact Hypersensitivity in Albino Guinea Pigs, Buehler Test; | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Methyltrimethoxysilane Contact Hypersensitivity in Albino Guinea Pigs, Buehler Test; | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish) | Author: Hazleton Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish) | Author: Hazleton Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of trimethoxy(methyl)silane | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of trimethoxy(methyl)silane | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2.; QSAR Prediction Reporting Format (QPRF) for the log Kow of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2.; QSAR Prediction Reporting Format (QPRF) for the log Kow of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of methylsilanetriol | Year: 2014; 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of trimethoxy(methyl)silane | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of trimethoxy(methyl)silane | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: SKIN SENSITISATION PROPERTIES OF TRIMETHOXY(METHYL)SILANE (CAS No. 1185-55-3) – EXPERIENCE IN HUMAN BEINGS | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Sensitisation data (humans) | Right to refer to study -- Title: SKIN SENSITISATION PROPERTIES OF TRIMETHOXY(METHYL)SILANE (CAS No. 1185-55-3) – EXPERIENCE IN HUMAN BEINGS | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Sensitization from Silquest A-1630 silane (trimethoxy(methyl)silane, CAS# 1185-55-3) and Silquest A-171 (trimethoxy(vinyl)silane, CAS# 2768-02-7) since production start-up in 1996. | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Sensitisation data (humans) | Right to refer to study -- Title: Sensitization from Silquest A-1630 silane (trimethoxy(methyl)silane, CAS# 1185-55-3) and Silquest A-171 (trimethoxy(vinyl)silane, CAS# 2768-02-7) since production start-up in 1996. | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of Skin Sensitization to Trimethoxy(methyl)silane (CAS number 1185-55-3) in the Mouse (Local Lymph Node Assay) | Year: 2021 | Guideline: B.42, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Assessment of Skin Sensitization to Trimethoxy(methyl)silane (CAS number 1185-55-3) in the Mouse (Local Lymph Node Assay) | Year: 2021 | Guideline: B.42, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |