You are here: Home> Turkey>TR-REACH>CAS 121-32-4> CAS 121-32-4 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Determination of the particle size distribution of diphenols | Author: Masson J.C. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Budavari S. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Lide D.R. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Food Additives 2nd ed. vol 2. | Author: Weast R.C. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Données de sécurité : Rhodiarome extra pure | Author: Vibert M. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Données de sécurité : Rhodiarome extra pure | Author: Vibert M. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Flavor or Fragrance Ingredient Data Set. Ethyl vanillin [CAS n°121-32-4] | Author: FMA | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Fenaroli's Handbook of Flavor Ingredients | Author: No author provided | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: SRC Physprop. Physical and chemical properties database | Author: No author provided | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: National Library of Medecine; ChemIDplus advance | Author: No author provided | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Relative Density - Stereopycnometer method of ETHYLVANILLINE (121-32-4) In compliance with Commission Regulation (EC) No. 440/2008 EC A3 method (2008) OECD Guideline No 109 (1995) | Author: Demangel B. | Year: 2011 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Relative Density - Stereopycnometer method of ETHYLVANILLINE (121-32-4) In compliance with Commission Regulation (EC) No. 440/2008 EC A3 method (2008) OECD Guideline No 109 (1995) | Author: Demangel B. | Year: 2011 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of the vapour pressure of ETHYLVANILLINE (121-32-4) In compliance with Commission Regulation (EC) No. 761/2009 EC A4 method (2009) and OECD Guideline No. 104 (2006) | Author: Demangel B. | Year: 2011 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of the vapour pressure of ETHYLVANILLINE (121-32-4) In compliance with Commission Regulation (EC) No. 761/2009 EC A4 method (2009) and OECD Guideline No. 104 (2006) | Author: Demangel B. | Year: 2011 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Yaws C.L. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Flavor or Fragrance Ingredient Data Set. Ethyl vanillin [CAS n°121-32-4] | Author: FMA | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Prediction of partitioning properties of benzaldehydes by various molecular descriptors | Author: Jin L.J. et al. | Year: 1998 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: No author provided | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Relación entre el coeficiente de reparto (logPo/w) y el factor de capacidad (logK') derivado de la cromatografía liquida de alta resolución en fase inversa para una serie de derivados del aldehído benzoico | Author: Bazaco F.J. & Coca M.C. | Year: 1989 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: The relative toxicity of substituted phenols reported in cigarette mainstream smoke. | Author: Smith C.J. et al. | Year: 2002 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Prediction of partition coefficent and toxicity for benzaldehyde compounds by their capacity factors and various molecular descriptors | Author: Dai J. et al. | Year: 2001 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Prediction of partitioning properties of benzaldehydes by various molecular descriptors | Author: Jin L.J. et al. | Year: 1998 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination and estimation of the sorption of benzaldehydes on soil | Author: Jin L.J. et al. | Year: 1997 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation Programs Interface Suite™ for Microsoft® Windows v 4.00: KOWWIN v1.67 | Author: US EPA | Year: 2011 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Determination of the particle size distribution of diphenols | Author: Masson J.C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Determination of the particle size distribution of diphenols | Author: Masson J.C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Données de sécurité : Rhodiarome extra pur | Author: Vibert M. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Données de sécurité : Rhodiarome extra pur | Author: Vibert M. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute dermal irritation in rabbits | Author: Klein E. | Year: 2003 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute dermal irritation in rabbits | Author: Klein E. | Year: 2003 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Evaluation of skin sensitization potential in mice using the local lymph node assay (LLNA) | Author: Klein E. | Year: 2003 | Guideline: 406, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Evaluation of skin sensitization potential in mice using the local lymph node assay (LLNA) | Author: Klein E. | Year: 2003 | Guideline: 406, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Human potency predictions for aldehydes using the local lymph node assay. | Author: Basketter D.A. et al. | Year: 2001 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Evaluation of the Mutagenic Activity of 3-ethoxy-4-hydroxybenzaldehyde (Ethylvanillin) in the Salmonella typhimurium Reverse Mutation Assay and the Escherichia coli Reverse Mutation Assay (Plate Incorporation and Pre-Incubation Methods) | Author: Gijsbrechts J.J.A. | Year: 2017 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Evaluation of the Mutagenic Activity of 3-ethoxy-4-hydroxybenzaldehyde (Ethylvanillin) in the Salmonella typhimurium Reverse Mutation Assay and the Escherichia coli Reverse Mutation Assay (Plate Incorporation and Pre-Incubation Methods) | Author: Gijsbrechts J.J.A. | Year: 2017 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Primary mutagenicity screening of food additives currently used in Japan. | Author: Ishidate Jr. M. et al. | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: No information | Author: NTP | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals | Author: Mortelman K. et al. | Year: 1986 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity evaluation of ethyl vanillin in the Ames Salmonella/microsone plate test. | Author: Research Institute for Fragrance Materials Inc | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity evaluation of ethyl vanillin in the Ames Salmonella/microsone plate test. | Author: Research Institute for Fragrance Materials Inc | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Test to evaluate the acute toxicity following a single oral administration (LD 50) in the rat | Author: Lheritier M. | Year: 1992 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Test to evaluate the acute toxicity following a single oral administration (LD 50) in the rat | Author: Lheritier M. | Year: 1992 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Identification of coumarin as the sensitizer in a patient sensitive to her own perfume but negative to the fragrance mix. | Author: Mutterer V. et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Patch testing with fragrances: Results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes. | Author: Frosch P.J. et al. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicities of organic chemicals to fathead minnow (Pimephales promelas) | Author: Brooke L.T. et al. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute oral Toxicity of 1496 chemicals forced-fed to carp. U.S fish | Author: Loeb H.A. & Kelly W.H. | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: aquatic test #: 64132 | Author: US EPA | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: 3-ethoxy-4-hydroxybenzaldehyde (ethylvanillin): A Study on the Acute Toxicity to Daphnia magna according to OECD Guidelines for Testing of Chemicals Guideline 202 "Daphnia sp. Acute Immobilisation Test" | Author: Philipp Egeler | Year: 2017 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: 3-ethoxy-4-hydroxybenzaldehyde (ethylvanillin): A Study on the Acute Toxicity to Daphnia magna according to OECD Guidelines for Testing of Chemicals Guideline 202 "Daphnia sp. Acute Immobilisation Test" | Author: Philipp Egeler | Year: 2017 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Effect of Vanillin on the reproduction of Daphnia magna | Author: Källqvist T. | Year: 1996 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 121-33-5 | EC 204-465-2 | 4-hydroxy-3-methoxybenzaldehyde ) |
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| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Effect of Vanillin on the reproduction of Daphnia magna | Author: Källqvist T. | Year: 1996 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 121-33-5 | EC 204-465-2 | 4-hydroxy-3-methoxybenzaldehyde ) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: No information | Author: MITI | Year: 2002 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Estimation Programs Interface Suite™ for Microsoft® Windows v 4.0: BIOWWIN v4.10 | Author: US EPA | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |