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CAS 127-18-4 | Data Package 1 - 10 t/a

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Includes:

Study name Short Description Data Owner
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: Odour as an aid to chemical safety odour thresholds compared with threshold limit values and volatilities for 214 industrial chemicals in air and water dilution. | Author: Amoore J.E., Hautala E. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: The Merck Index | Author: Budaveri S.) | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: The Merck Index | Author: Budaveri S.) | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: The Physical Properties of Some Aliphatic Compounds. | Author: Mumford S.A., Phillips J.W.C. | Year: 1950 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: The Physical Properties of Some Aliphatic Compounds. | Author: Mumford S.A., Phillips J.W.C. | Year: 1950 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: No information | Author: No author provided | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Surface tension Robust Study Summary -- Title: The Physical Properties of Some Aliphatic Compounds. | Author: Mumford S.A., Phillips J.W.C. | Year: 1950 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: No information | Author: Mackay D., Shiu W.Y., Ma K.C. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Water Solubility and Octanol/Water Partition Coefficient of Organics. Limitations of the Solubility-Partition Coefficient Correlation. | Author: Banerjee S., Yalkowsky S.H., Valvani S.C. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: An evaluation of using partition coefficients and water solubility to estimate bioconcentration factors for organic chemicals in fish. | Author: Veith G.D. et al. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Flash point Robust Study Summary -- Title: The Merck Index | Author: Budavari S. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Budaveri S. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane trichloroethylene tetrachloroethylene and 111-trichloroethane | Author: Van Beek L. | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane trichloroethylene tetrachloroethylene and 111-trichloroethane | Author: Van Beek L. | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Assessment of contact hypersensitivity to tetrachloroethylene in the mouse (local lymph node assay) | Author: NOTOX B.V. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Right to refer to study -- Title: Assessment of contact hypersensitivity to tetrachloroethylene in the mouse (local lymph node assay) | Author: NOTOX B.V. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Genotoxicity of organic chemicals frequently found in the air of mobile homes | Author: Connor T.H. et al. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagencity of tetrachloroethylene in the Ames test. Metabolic activation by conjugation with glutathione | Author: Vamvakas S. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Identification and mutagenic properties of some chlorinated aliphatic compounds in the spent liquor from Kraft pulp chlorination | Author: Kringstad K.P. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: The subchronic toxicity of tetrachloroethylene (perchloroethylene) administered in the drinking water of rats | Author: Hayes J.R. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: European Union Risk Assessment Report: Tetrachloroethylene CAS No 127-18-4 EINECS No 204-825-9. Final draft human health report for publication | Author: Rapporteur: United Kingdom on behalf of the European Union | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute and chronic toxicity of some chlorinated benzenes chlorinated ethanes and tetrachloroethylene to Daphnia magna | Author: Richter J.E., Peterson S.F., Kleiner C.F. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Toxicity and metabolism studies with EPA priority pollutants and related chemicals in freshwater organisms | Author: Call D.J. et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Ergbnisse der Untersuchungen von chemischen Stoffen mit vier Biotests | Author: Knie J. et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Toxicity screening of fifteen chlorinated and brominated compounds using four species of marine plankton. Environmental impact and health effects | Author: Erickson S.J., Freeman A.E. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Toxicity testing of highly volatile chemicals with green algae - A new assay | Author: Brack W., Rottler H. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Anaerobic bacteria that dechlorinate perchloroethene | Author: Fathepure B.Z. et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Dependence of tetrachloroethylene dechlorination on methanogenic substrate consumption by Methanosarcina sp. strain DCM. | Author: Fathepure B.Z., Boyd S.A. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Reductive dechlorination of tri- and tetrachloroethylenes depends on transition from aerobic to anaerobic conditions | Author: Kästner M. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biotransformation of tetrachloroethylene to trichloroethylene dichloroethylene vinyl chloride and carbon dioxide under methanogenic conditions | Author: Vogel T.M., McCarty P.L. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Data of existing chemicals based on the CSCL Japan: biodegradation and bioaccumulation | Author: CSCL | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: European Union Risk Assessment Report - TETRACHLOROETHYLENE | Author: EU RAR | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradability studies with organic priority pollutant compounds | Author: Tabak H.H. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Development of empirical structure biodegradability relationships and biodegradability testing protocol for volatile and slightly soluble priority pollutants | Author: Mudder T.I., Musterman J.L. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biological reductive dechlorination of tetrachloroethylene and trichloroethylene to ethylene under methanogenic conditions | Author: Freedman D.L., Gosset J.M. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biotransformation of chlorinated aliphatic solvents in the presence of aromatic compounds under methanogenic conditions | Author: Liang .LN., Grbic -Galic D. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: A highly purified enrichment culture couples the reductive dechlorination of tetrachloroethylene to growth | Author: Holliger C. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Reductive dechlorination of high concentrations of tetrachloroethylene to ethene by an anaerobic enrichment culture in the absence of methanogenesis | Author: DiStefano T.D., Gossett J.M., Zinder S.H. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Hydrogen as an electron donor for dechlorination of tetrachloroethylene by an anaerobic mixed culture | Author: DiStefano T.D., Gossett J.M., Zinder S.H. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -