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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Dipropylene glycol: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Dipropylene glycol: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Glycols | Author: Brown ES Hauser CF Ream BC Berthold RV | Year: 1980 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Dipropylenglycol | Author: Hommel G | Year: 1983 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physical properties of hydrocarbons XIV. Glycols and glycerin | Author: Gallant RW | Year: 1967 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Glycols | Author: Brown E. S.; Hauser C. F.; Ream B. C.; Berthold R.V. | Year: 1980 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Propandiole. | Author: Elm R.; Falbe J.; Hahn H.-D.; Gelbke H.-P. | Year: 1980 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Dipropylene glycol | Author: Browning E | Year: 1965 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Glycols | Author: Brown E. S.; Hauser C. F.; Ream B. C.; Berthold R.V. | Year: 1980 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dipropylene glycol | Author: Browning E | Year: 1965 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Propandiole. | Author: Elm R.; Falbe J.; Hahn H.-D.; Gelbke H.-P. | Year: 1980 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Water quality characteristics of hazardous materials | Author: Hann RW Jr Jensen PA | Year: 1977 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface Tension | Robust Study Summary -- Title: KOWWIN v.167 http://www.epa.gov/oppt/exposure/pubs/episuite.htm | Author: U.S. Environmental Protection Agency | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Glycols. | Author: Brown ES Hauser CF Ream BC Berthold RV | Year: 1980 | Guideline: 114 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Glycols. | Author: Brown E. S.; Hauser C. F.; Ream B. C.; Berthold R.V. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Propandiole. | Author: Elm R.; Falbe J.; Hahn H.-D.; Gelbke H.-P. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: A.15-16 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: A.15-16 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Propandiole. | Author: Elm R Falbe J Hahn H-D Gelbke H-P | Year: 1980 | Guideline: A.15-16 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: NITE | Year: 2009 | Guideline: A.15-16 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity study of dipropylene glycol in the Ames Salmonella/microsome plate test (in vitro) | Author: LPT Laboratory of Pharmacology and Toxicology | Year: 1992 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity study of dipropylene glycol in the Ames Salmonella/microsome plate test (in vitro) | Author: LPT Laboratory of Pharmacology and Toxicology | Year: 1992 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Test for chemical induction of mutation in mammalian cells in sulture the L5178Y TK+/- - mouse lymphoma assay | Author: SITEK Research Laboratories | Year: 1988 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Test for chemical induction of mutation in mammalian cells in sulture the L5178Y TK+/- - mouse lymphoma assay | Author: SITEK Research Laboratories | Year: 1988 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Evaluation of dipropylene glycol in the mouse bone marrow micronucleus test | Author: Dow Chemical Company | Year: 1999 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Evaluation of dipropylene glycol in the mouse bone marrow micronucleus test | Author: Dow Chemical Company | Year: 1999 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Determination of the acute oral toxicity of dipropylene glycol in rats | Author: CIVO-TNO Dept. Biological Toxicology | Year: 1980 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Determination of the acute oral toxicity of dipropylene glycol in rats | Author: CIVO-TNO Dept. Biological Toxicology | Year: 1980 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism of Tripropylene Glycol in Rats | Author: Dow Chemical Company | Year: 1995 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolism of Tripropylene Glycol in Rats | Author: Dow Chemical Company | Year: 1995 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: A comparison of rat chronic progressive nephropathy with human renal disease-implications for human risk assessment. | Author: Hard GC Johnson KJ Cohen SM | Year: 2009 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity evaluation of dipropylene glycol (CAS No. 25265-71-8) administered to Sprague-Dawley (CD) rats from gestation day 6 through gestation day 15 | Author: NTP TER-92-013 | Year: 1990 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity evaluation of dipropylene glycol (CAS No. 25265-71-8) administered by gavage to New Zealand White rabbits from gestation day 6 through gestation day 19 | Author: NTP TER-92-014 | Year: 1990 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Results and evaluations of 48 continuous breeding reproduction studies conducted in mice | Author: Morrissey RE Lamb IV JC Morris RW Chapin RE Gulati DK Heindel JJ | Year: 1989 | Guideline: 421 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: NTP Technical Report on the toxicology and carcinogenesis studies of dipropylene glycol (CAS No. 25265-71-8) in F344/N rats and B6C3F1 mice (drinking water studies) | Author: National Toxicology Program | Year: 2004 | Guideline: 451, 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Evaluation of the acute toxicity of industrial grade propylene glycol to representative freshwater organisms | Author: The Dow Chemical Company | Year: 1993 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Evaluation of the acute toxicity of industrial grade propylene glycol to representative freshwater organisms | Author: The Dow Chemical Company | Year: 1993 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: SIDS Initial Assessment Report for Tripropylene glycol | Author: OECD | Year: 1994 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: ECOSAR v1.00 | Author: U.S. Environmental Protection Agency | Year: 2009 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Dipropylene Glycol - Determination of the acute effect on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Dipropylene Glycol - Determination of the acute effect on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: ECOSAR v1.00 | Author: U.S. Environmental Protection Agency | Year: 2009 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Dipropylene Glycol - Determination of the inhibitory effect on the cell multiplication of unicellular green algae | Author: BASF | Year: 2002 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Dipropylene Glycol - Determination of the inhibitory effect on the cell multiplication of unicellular green algae | Author: BASF | Year: 2002 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: ECOSAR v1.00 | Author: U.S. Environmental Protection Agency | Year: 2009 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Bestimmung der akuten Bakterientoxizitaet an Pseudomonas putida | Author: NATEC Institut fuer naturwissenschaftlich-technische Dienste GmbH | Year: 1992 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Bestimmung der akuten Bakterientoxizitaet an Pseudomonas putida | Author: NATEC Institut fuer naturwissenschaftlich-technische Dienste GmbH | Year: 1992 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: ECOSAR v1.00 | Author: U.S. Environmental Protection Agency | Year: 2009 | Guideline: 210 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: ECOSAR v1.00 | Author: U.S. Environmental Protection Agency | Year: 2009 | Guideline: 211 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Dipropylene glycol. Chemicals inspection & testing institute Japan: Data of existing chemicals based on the CSCL Japan. | Author: MITI | Year: 1992 | Guideline: 305 C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradability relationships among propylene glycol substances in the organization for economic cooperation and development read- and seawater biodegradability tests. | Author: West RJ Davis JW Pottenger LH Banton MI Graham C | Year: 2007 | Guideline: 301 F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dipropylene glycol: An assessment of inherent biodegradability in the modified SCAS test | Author: Sittingbourne Research Centre | Year: 1994 | Guideline: 302A | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Dipropylene glycol: An assessment of inherent biodegradability in the modified SCAS test | Author: Sittingbourne Research Centre | Year: 1994 | Guideline: 302A | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Technical Guidance Document on Risk Assessment | Author: ECB | Year: 2003 | Guideline: 106 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Propylene Glycol-derived materials: evaluation of biodegradability in seawater according to OECD guideline 306 | Author: Envrionmental Chemistry Research Laboratory | Year: 2004 | Guideline: 306 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Right to refer to study -- Title: Propylene Glycol-derived materials: evaluation of biodegradability in seawater according to OECD guideline 306 | Author: Envrionmental Chemistry Research Laboratory | Year: 2004 | Guideline: 306 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Biodegradability relationships among propylene glycol substances in the Organization for Economic Cooperation and Development ready- and seawater biodegradability tests. | Author: West RJ et.al. | Year: 2007 | Guideline: 306 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 107/117/122/123 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 107/117/122/123 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: KOWWIN v.167 http://www.epa.gov/oppt/exposure/pubs/episuite.htm | Author: U.S. Environmental Protection Agency | Year: 2000 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |