You are here: Home> Turkey>TR-REACH>CAS 26471-62-5> CAS 26471-62-5 | Data Package 100 - 1000 t/a (Affiliates of III)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Tolylene-2,4/2,6-diisocyanate mixture (65:35-TDI): determination of physicochemical properties. | Author: Fisk P.R. & Langner E.J. | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Toluene di-isocyanate: an evaluation in the mouse micronucleus test | Author: MacKay J.M. | Year: 1992 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Toluene diisocyanate: acute inhalation toxicity in the rat | Author: Doe J.E. & Horspool G.M. | Year: 1980 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Pharmacokinetics of TDI after inhalation exposure of rats to labelled TDI | Author: Saclay | Year: 1977 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Two-generation reproduction study of inhaled toluene diisocyanate in CD (Sprague-Dawley) rats | Author: Tyl R.W. & Neeper-Bradley T.L. | Year: 1989 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Ecotoxicities of TDI and TDA to fish algae and aquatic invertebrates | Author: Tadokoro H. Nozaka T. Hirata S. & Tounai T. | Year: 1997 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Ecotoxicities of TDI and TDA to fish algae and aquatic invertebrates | Author: Tadokoro H. Nozaka T. Hirata S. & Tounai T. | Year: 1997 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Ecotoxicities of TDI and TDA to fish algae and aquatic invertebrates | Author: Tadokoro H. Nozaka T. Hirata S. & Tounai T. | Year: 1997 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Ecotoxicity of toluenediiosycanate (TDI) diphenylmethanediisocyanate (MDI) toluenediamine (TDA) and diphenylmethanediamine (MDA) | Author: Caspers N. Hamburger B. Kanne R. & Klebert W. | Year: 1986 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Determination of the effect of TDI on the reproduction of Daphnia magna | Author: Cerbelaud E. Saugues M. Cellier P. & Argoud M. | Year: 1997 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to soil macro-organisms except anthropods | Right to refer to study -- Title: Determination of the LC50 (14 days) of TDI TDA MDI and MDA to the earthworm Eisenia fetida according to OECD guideline no. 207 | Author: van der Hoeven N. Roza P. & Henzen L. | Year: 1992 | Guideline: 207 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Right to refer to study -- Title: The bioconcentration of 2,4-TDI in Cyprinus carpio: Test Number 50311 | Author: CERI | Year: 2003 | Guideline: 305E | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: A study of the fate of TDI in water. Effect of interfacial area under static condition | Author: Yakabe Y. Mori E. & Tadokoro H | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |