You are here: Home> Turkey>TR-REACH>CAS 53880-05-0> CAS 53880-05-0 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Safety data sheet "Vestanat T 1890/100", Version 6.5/DE | Author: Evonik Degussa GmbH | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane / 4098-71-9 / 223-861-6; Isophorone diisocyanate homopolymer (53880-05-0; 4098-71-9)) |
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| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Safety data sheet "Vestanat T 1890/100", Version 6.5/DE | Author: Evonik Degussa GmbH | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane / 4098-71-9 / 223-861-6; Isophorone diisocyanate homopolymer (53880-05-0; 4098-71-9)) |
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| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Determination of the melting point / boiling point of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Determination of the melting point / boiling point of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Determination of the glass transition temperature of Vestanat T 1890/100 | Author: Steinheuer A | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Determination of the glass transition temperature of Vestanat T 1890/100 | Author: Steinheuer A | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Determination of the melting point / boiling point of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Boiling point | Right to refer to study -- Title: Determination of the melting point / boiling point of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Density | Robust Study Summary -- Title: Determination of the relative density of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Density | Right to refer to study -- Title: Determination of the relative density of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of the vapour pressure of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of the vapour pressure of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Partition coefficient | Waiver | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Physikalisch-chemische Daten und Verbleib von Isophorondiisocyanat, Homopolymer | Author: Evonik Degussa GmbH | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 67873-91-0 | EC 267-445-2 | 1,3,5-tris[(5-isocyanato-1,3,3-trimethylcyclohexyl)methyl]-1,3,5-triazinane-2,4,6-trione) |
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| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Physikalisch-chemische Daten und Verbleib von Isophorondiisocyanat, Homopolymer | Author: Evonik Degussa GmbH | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 67873-91-0 | EC 267-445-2 | 1,3,5-tris[(5-isocyanato-1,3,3-trimethylcyclohexyl)methyl]-1,3,5-triazinane-2,4,6-trione) |
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| Phys-Chem | Water solubility | Waiver | - |
| Phys-Chem | Surface tension | Waiver | - |
| Phys-Chem | Flash point | Waiver | - |
| Phys-Chem | Auto-ignition temperature | Waiver | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Determination of the flammability of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Flammability | Right to refer to study -- Title: Determination of the flammability of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of the explosion properties of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of the explosion properties of Vestanat T 1890/100 | Author: AQura GmbH | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Phys-Chem | Oxidising properties | Waiver | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: IPDI trimer - biodegradation | Author: Weyers A | Year: 2007 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: IPDI trimer - biodegradation | Author: Weyers A | Year: 2007 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Environmental | Other distribution data | Waiver | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: DESMODUR Z 4470 MPA/X Acute Immobilisation Test (48 h) to Daphnia magna STRAUS | Author: Noack A | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: DESMODUR Z 4470 MPA/X Acute Immobilisation Test (48 h) to Daphnia magna STRAUS | Author: Noack A | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: DESMODUR Z 4470 MPA/X Alga, Growth Inhibition Test with Scenedesmus subspicatus, 72 h, Limit-Test | Author: Scheerbaum D | Year: 2002 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: DESMODUR Z 4470 MPA/X Alga, Growth Inhibition Test with Scenedesmus subspicatus, 72 h, Limit-Test | Author: Scheerbaum D | Year: 2002 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Akute Toxizitätsprüfung von IPDI-Addukt T 1890 nach oraler Applikation an der Ratte | Author: IBR International Bio-Research | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Akute Toxizitätsprüfung von IPDI-Addukt T 1890 nach oraler Applikation an der Ratte | Author: IBR International Bio-Research | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Akute orale Toxizität - Prüfmuster: Desmodur VP KL 5-2426 | Author: Bayer AG | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: other information | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Akute orale Toxizität - Prüfmuster: Desmodur VP KL 5-2426 | Author: Bayer AG | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: other information | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Desmodur Z 4470 MPA/X - local lymph node assay in mice (LLNA/IMDS) | Author: Vohr HW | Year: 2003 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Desmodur Z 4470 MPA/X - local lymph node assay in mice (LLNA/IMDS) | Author: Vohr HW | Year: 2003 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of contact hypersensitivity to Vestanat T 1890 SV in the albino guinea pig (maximisation-test) | Author: NOTOX B.V. | Year: 2004 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Assessment of contact hypersensitivity to Vestanat T 1890 SV in the albino guinea pig (maximisation-test) | Author: NOTOX B.V. | Year: 2004 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Cutaneous sensitization to some polyisocyanate prepolymers in guinea pigs | Author: Zissu D, Binet S and Limasset JC | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Prüfung von "IPDI-T 1890" im epicutanen Sensibilisierungstest an der Meerschweinchenhaut (25 %ig in Sojabohnenöl) | Author: IBR International Bio-Research | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Prüfung von "IPDI-T 1890" im epicutanen Sensibilisierungstest an der Meerschweinchenhaut (25 %ig in Sojabohnenöl) | Author: IBR International Bio-Research | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Polyisocyanat IPDI-T 1890S (monomeres IPDI: < 0,5 Gew. %) - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäẞ OECD Richtlinien) | Author: IBR International Bio-Research | Year: 1983 | Guideline: 406 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Polyisocyanat IPDI-T 1890S (monomeres IPDI: < 0,5 Gew. %) - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäẞ OECD Richtlinien) | Author: IBR International Bio-Research | Year: 1983 | Guideline: 406 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Polyisocyanat IPDI-T 1890S (monomeres IPDI: 2 Gew. %) - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäẞ OECD Richtlinien) | Author: IBR International Bio-Research | Year: 1983 | Guideline: 406 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Polyisocyanat IPDI-T 1890S (monomeres IPDI: 2 Gew. %) - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäẞ OECD Richtlinien) | Author: IBR International Bio-Research | Year: 1983 | Guideline: 406 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of contact hypersensitivity to polyisocyanate resin 95222660 in the albino guinea pig (maximization test) | Author: NOTOX B.V. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: other information. Read-Across (Polyisocyanate resin 95222660) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Assessment of contact hypersensitivity to polyisocyanate resin 95222660 in the albino guinea pig (maximization test) | Author: NOTOX B.V. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: other information. Read-Across (Polyisocyanate resin 95222660) |
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| Toxicological | Skin sensitisation | Waiver | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella typhimurium and Escherichia coli reverse mutation assay with Oligomerization product (isocyanurate type) of isophorone diisocyanate | Author: Harlan CCR | Year: 2009 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella typhimurium and Escherichia coli reverse mutation assay with Oligomerization product (isocyanurate type) of isophorone diisocyanate | Author: Harlan CCR | Year: 2009 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Desmodur Z 4470 MPA/X - special study - Ames-test screening | Author: Herbold B | Year: 2002 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Desmodur Z 4470 MPA/X - special study - Ames-test screening | Author: Herbold B | Year: 2002 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer / 53880-05-0 / 500-125-5; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate homopolymer, isocyanurate type 931-312-3 / 53880-05-0) |
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