You are here: Home> Europe>UK-REACH>CAS 541-02-6> CAS 541-02-6 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: The Merck Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: The Merck Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Dataon Organic Compounds 2nd. Ed. | Author: Weast R.C. Grasselli J.G. eds. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Handbook of Dataon Organic Compounds 2nd. Ed. | Author: Weast R.C. Grasselli J.G. eds. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Methylpolysiloxanes. | Author: Patnode W. Wilcock D.F. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Methylpolysiloxanes. | Author: Patnode W. Wilcock D.F. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology 3rd ed. | Author: Kirk-Othmer | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Encyclopedia of Chemical Technology 3rd ed. | Author: Kirk-Othmer | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Organo- Silicon Polymers. The Cyclic Dimethyl|Siloxanes. | Author: Hunter M.J. Hyde J.F. Warrick E.L. Fletcher H.J.| | Year: 1946 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Organo- Silicon Polymers. The Cyclic Dimethyl|Siloxanes. | Author: Hunter M.J. Hyde J.F. Warrick E.L. Fletcher H.J.| | Year: 1946 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Vapor Pressure of Pure Substances. | Author: Stull D.R. | Year: 1947 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Vapor Pressure of Pure Substances. | Author: Stull D.R. | Year: 1947 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. | Author: O'Neil M | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Handbook of Data on Organic Compounds 2nd. Ed. | Author: Weast R.C. Grasselli J.G. eds. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Handbook of Data on Organic Compounds 2nd. Ed. | Author: Weast R.C. Grasselli J.G. eds. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Vapor Pressures of Poly(dimethylsiloxane) Oligomers. | Author: Flaningam O.L. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Vapor Pressures of Poly(dimethylsiloxane) Oligomers. | Author: Flaningam O.L. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Vapor Liquid Critical Properties. A Supplement to Report Chem. 107 | Author: Ambrose D. | Year: 1983 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Vapor Liquid Critical Properties. A Supplement to Report Chem. 107 | Author: Ambrose D. | Year: 1983 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Raman Spectra of Low Molecular Weight Siloxanes. | Author: Slobodin Ya.M. Shmulyakovskii Ya.E. Rzhedzinsdaya K.A. | Year: 1955 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Raman Spectra of Low Molecular Weight Siloxanes. | Author: Slobodin Ya.M. Shmulyakovskii Ya.E. Rzhedzinsdaya K.A. | Year: 1955 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology 3rd ed. | Author: Kirk-Othmer | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Encyclopedia of Chemical Technology 3rd ed. | Author: Kirk-Othmer | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Saturated Vapor Pressures of|Polydiorganosiloxanes II. Polydimethylcyclosiloxanes. | Author: Ditsent V.E. Skorokhodov I.I. Terent'eva N.A. Zolotareva M.N. | Year: 1971 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Saturated Vapor Pressures of|Polydiorganosiloxanes II. Polydimethylcyclosiloxanes. | Author: Ditsent V.E. Skorokhodov I.I. Terent'eva N.A. Zolotareva M.N. | Year: 1971 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Methylpolysiloxanes. | Author: Patnode W. Wilcock D.F. | Year: 1946 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Methylpolysiloxanes. | Author: Patnode W. Wilcock D.F. | Year: 1946 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. Twelfth Edition. | Author: Merck | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. Twelfth Edition. | Author: Merck | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: The Handbook of Environmental Chemistry: Organosilicon Materials. | Author: Chandra G. Ed. | Year: 1997 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: The Handbook of Environmental Chemistry: Organosilicon Materials. | Author: Chandra G. Ed. | Year: 1997 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physical Property Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physical Property Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Measurement of Thermophysical Pure Component Properties for a Fee Siloxanes Used as Working Fluids for Organic Rankine Cycles | Author: Abbas R Schedemann A Ihmels C Enders S Gmehling J | Year: 2011 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Measurement of Thermophysical Pure Component Properties for a Fee Siloxanes Used as Working Fluids for Organic Rankine Cycles | Author: Abbas R Schedemann A Ihmels C Enders S Gmehling J | Year: 2011 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Temperature-Dependent Vapor Pressure of Selected Cyclic and Linear Polydimethylsiloxane Oligomers | Author: Lei Y D Wania F Mathers D | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Temperature-Dependent Vapor Pressure of Selected Cyclic and Linear Polydimethylsiloxane Oligomers | Author: Lei Y D Wania F Mathers D | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapour pressure of poly(dimethylsiloxane) oligomers. | Author: Flaningam O L | Year: 1986 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapour pressure of poly(dimethylsiloxane) oligomers. | Author: Flaningam O L | Year: 1986 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapour pressure of poly(dimethylsiloxane) oligomers. | Author: Flaningam O.L. | Year: 1986 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapour pressure of poly(dimethylsiloxane) oligomers. | Author: Flaningam O.L. | Year: 1986 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Organosilicon materials. | Author: Chandra G | Year: 1997 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Organosilicon materials. | Author: Chandra G | Year: 1997 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. Twelfth Edition. | Author: Merck | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: The MERCK Index. An encyclopedia of chemicals drugs and biologicals. Twelfth Edition. | Author: Merck | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Aqueous Solubility of Permethylsiloxanes (Silicones). | Author: Varaprath S.; Frye C.; Hamelink J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Aqueous Solubility of Permethylsiloxanes (Silicones). | Author: Varaprath S.; Frye C.; Hamelink J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Simultaneous Determination of Partition Coefficients for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane. | Author: Xu S Kropscott B | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Simultaneous Determination of Partition Coefficients for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane. | Author: Xu S Kropscott B | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (D5) by the Slow-Stirring Method Using Gas Chromogratography and Mass Spectrometry. | Author: Kozerski G E Shawl H R | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (D5) by the Slow-Stirring Method Using Gas Chromogratography and Mass Spectrometry. | Author: Kozerski G E Shawl H R | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (d5) by the Slow-Stirring Method Using Gas Chromatography and Mass Spectrometry | Author: Dow Corning Corporation | Year: 2007 | Guideline: 123 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (d5) by the Slow-Stirring Method Using Gas Chromatography and Mass Spectrometry | Author: Dow Corning Corporation | Year: 2007 | Guideline: 123 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: 1-Octanol/Air Partitioning Coefficients of Octamethylcyclotetrasiloxane (D4) Decamethylcyclopentasiloxane (D5) and Dodecamethylcyclohexasiloxane (D6) at Different Temperatures. | Author: Xu S | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: 1-Octanol/Air Partitioning Coefficients of Octamethylcyclotetrasiloxane (D4) Decamethylcyclopentasiloxane (D5) and Dodecamethylcyclohexasiloxane (D6) at Different Temperatures. | Author: Xu S | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Process Safety Test Results and Interpretation for Decamethylcyclopentasiloxane 97% | Author: Chilworth Technology Inc. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Process Safety Test Results and Interpretation for Decamethylcyclopentasiloxane 97% | Author: Chilworth Technology Inc. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Safety Data Sheet | Author: Bayer AG | Year: 2004 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Safety Data Sheet | Author: Bayer AG | Year: 2004 | Klimisch score: 4 (not assignable) | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Flash Point Autoignition Temperature and Lower and Upper Flammability Limits of Selected Silicon Intermediates-II. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary skin irritation study. | Author: Toxikon Corporation | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary skin irritation study. | Author: Toxikon Corporation | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Rabbit skin irritation (closed patch test) | Author: Proctor & Gamble | Year: 1985 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Rabbit skin irritation (closed patch test) | Author: Proctor & Gamble | Year: 1985 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Rabbit Skin Irritation (SL: V3948-107) | Author: Unknown | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Rabbit Skin Irritation (SL: V3948-107) | Author: Unknown | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Pr??fung auf prim??r reizende Wirkung an der Kaninchenhaut (Baysilone-??l VP AC 3060) | Author: Bayer AG | Year: 1983 | Guideline: 404 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Pr??fung auf prim??r reizende Wirkung an der Kaninchenhaut (Baysilone-??l VP AC 3060) | Author: Bayer AG | Year: 1983 | Guideline: 404 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Primary ocular irritation. | Author: Toxikon Corporation | Year: 1990 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Primary ocular irritation. | Author: Toxikon Corporation | Year: 1990 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Draize eye irritation of the test material T7095 in rabbits | Author: Springborn Institute for Bioresearch Inc | Year: 1977 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Draize eye irritation of the test material T7095 in rabbits | Author: Springborn Institute for Bioresearch Inc | Year: 1977 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Miscellaneous Toxicity Studies | Author: Carnegie-Mellon | Year: 1976 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Miscellaneous Toxicity Studies | Author: Carnegie-Mellon | Year: 1976 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Pr??fung auf prim??r reizende Wirkung an der Kaninchenhaut (Baysilone-??l VP AC 3060) | Author: Bayer AG | Year: 1983 | Guideline: 405 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Pr??fung auf prim??r reizende Wirkung an der Kaninchenhaut (Baysilone-??l VP AC 3060) | Author: Bayer AG | Year: 1983 | Guideline: 405 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Pr??fung auf prim??r reizende/??tzende Wirkung am Kaninchenauge (Baysilone-??l VP AC 3060) | Author: Suberg H | Year: 1983 | Guideline: 405 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Pr??fung auf prim??r reizende/??tzende Wirkung am Kaninchenauge (Baysilone-??l VP AC 3060) | Author: Suberg H | Year: 1983 | Guideline: 405 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Test for sensitisation (Local Lymph Node Assay - LLNA) with 1111-19-372 | Author: BSL Bioservice Scientific Labs | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (87% 541-02-6 and 13% 443892-05-5; 87% Decamethylcyc1opentasiloxane 13% Silicone Gel) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Test for sensitisation (Local Lymph Node Assay - LLNA) with 1111-19-372 | Author: BSL Bioservice Scientific Labs | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (87% 541-02-6 and 13% 443892-05-5; 87% Decamethylcyc1opentasiloxane 13% Silicone Gel) |
- |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Kligman maximisation test - modified | Author: Toxikon Corporation | Year: 1998 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Kligman maximisation test - modified | Author: Toxikon Corporation | Year: 1998 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Kligman maximisation test - modified | Author: Toxikon Corporation | Year: 1998 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Kligman maximisation test - modified | Author: Toxikon Corporation | Year: 1998 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Buehler Topical Closed Patch Technique | Author: Toxikon Corporation | Year: 1990 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Buehler Topical Closed Patch Technique | Author: Toxikon Corporation | Year: 1990 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Pr??fung auf sensibilisierende Wirkung ander Meerschweinchenhaut. | Author: Bayer AG | Year: 1985 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Pr??fung auf sensibilisierende Wirkung ander Meerschweinchenhaut. | Author: Bayer AG | Year: 1985 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella typhimurium and Escherichia coli Reverse Mutation Assay with Decamethylcyclopentasiloxane (D5) | Author: RCC Cytotest cell research | Year: 2003 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella typhimurium and Escherichia coli Reverse Mutation Assay with Decamethylcyclopentasiloxane (D5) | Author: RCC Cytotest cell research | Year: 2003 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro Chromosome Aberration Test in Chinese Hamster V79 Cells with Decamethylcyclopentasiloxane (D5) | Author: Dow Corning Corporation | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro Chromosome Aberration Test in Chinese Hamster V79 Cells with Decamethylcyclopentasiloxane (D5) | Author: Dow Corning Corporation | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: studies on selected organosilicon compounds: in vitro assays | Author: Isquith A et al. | Year: 1988 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: studies on selected organosilicon compounds: in vitro assays | Author: Isquith A et al. | Year: 1988 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Genotoxicity studies on selected organosilicon compounds: in vitro assays. | Author: Isquith A et al. | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Genotoxicity studies on selected organosilicon compounds: in vitro assays. | Author: Isquith A et al. | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella/Microsomen Test zur Untersuchung auf Punktmutagene Wirkung | Author: Bayer | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella/Microsomen Test zur Untersuchung auf Punktmutagene Wirkung | Author: Bayer | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Evaluation of Dow Corning 345 Fluid in the Ames Bacterial Assay. | Author: Dow Corning Corporation | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Evaluation of Dow Corning 345 Fluid in the Ames Bacterial Assay. | Author: Dow Corning Corporation | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Genotoxicity studies on selected organosilicon compounds: in vitro assays. | Author: Isquith A et al. | Year: 1988 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Genotoxicity studies on selected organosilicon compounds: in vitro assays. | Author: Isquith A et al. | Year: 1988 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Mutagenicity Evaluation of Decamethylcyclopentasiloxane (Me2SiO)5 Final Report | Author: Litton Bionetics | Year: 1978 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity | Author: Toxikon Corporation | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity | Author: Toxikon Corporation | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: A study of the acute oral (LD50) toxicity of the test substance T7095 in rats | Author: Springborn Institute for Bioresearch Inc | Year: 1977 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: A study of the acute oral (LD50) toxicity of the test substance T7095 in rats | Author: Springborn Institute for Bioresearch Inc | Year: 1977 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range-finding toxicity data: List VIII | Author: Carpenter CP Weil CS Smyth Jr HF | Year: 1974 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range-finding toxicity data: List VIII | Author: Carpenter CP Weil CS Smyth Jr HF | Year: 1974 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Untersuchungen zur akuten oralen Toxizit??t an|m??nnlichen und weiblichen Wistar-Ratten. | Author: Bayer AG | Year: 1984 | Guideline: 401 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Untersuchungen zur akuten oralen Toxizit??t an|m??nnlichen und weiblichen Wistar-Ratten. | Author: Bayer AG | Year: 1984 | Guideline: 401 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: 4-Hour Acute Inhalation Toxicity Study with Decamethylcyclopentasiloxane in Rats | Author: RCC Ltd | Year: 1994 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: 4-Hour Acute Inhalation Toxicity Study with Decamethylcyclopentasiloxane in Rats | Author: RCC Ltd | Year: 1994 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Untersuchungen zur akuten|Inhalationstoxizität. | Author: Bayer AG | Year: 1984 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Untersuchungen zur akuten|Inhalationstoxizität. | Author: Bayer AG | Year: 1984 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute percutaneous toxicity in rabbits | Author: WIL Research Laboratories | Year: 1977 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute percutaneous toxicity in rabbits | Author: WIL Research Laboratories | Year: 1977 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Range-finding toxicity data: list VIII. | Author: Carpenter P et al. | Year: 1974 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Range-finding toxicity data: list VIII. | Author: Carpenter P et al. | Year: 1974 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Untersuchung zur akuten cutanen Toxizit??t an|m??nnlichen und weiblichen Wistar-Ratten. | Author: Bayer AG | Year: 1985 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Untersuchung zur akuten cutanen Toxizit??t an|m??nnlichen und weiblichen Wistar-Ratten. | Author: Bayer AG | Year: 1985 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and disposition of [14C]-methylcyclosiloxanes in rats | Author: Domoradzki JY Sushynski CM Sushynski JM McNett DA Landingham CV Plotzke KP | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolism and disposition of [14C]-methylcyclosiloxanes in rats | Author: Domoradzki JY Sushynski CM Sushynski JM McNett DA Landingham CV Plotzke KP | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition and Pharmacokinetics of 14C-Decamethylcyclopentasiloxane (14C-D5) following Single Oral Gavage Administration to Fischer 344 Rats in a Liquid Diet Vehicle | Author: Dow Corning Corporation | Year: 2012 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Disposition and Pharmacokinetics of 14C-Decamethylcyclopentasiloxane (14C-D5) following Single Oral Gavage Administration to Fischer 344 Rats in a Liquid Diet Vehicle | Author: Dow Corning Corporation | Year: 2012 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Absorption distribution metabolism and excretion (ADME) study of decamethylcyclopentasiloxane (D5) in the rat following a 14-day nose-only vapour inhalation exposure to D5 followed by a single nose-only vapour inhalation exposure to 14C-D5 on day 15. | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Absorption distribution metabolism and excretion (ADME) study of decamethylcyclopentasiloxane (D5) in the rat following a 14-day nose-only vapour inhalation exposure to D5 followed by a single nose-only vapour inhalation exposure to 14C-D5 on day 15. | Author: Dow Corning Corporation | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: ADME Study of 14C D5 in the Rat following a Single Nose-only Vapor Inhalation Exposure to 14C-D5 at Two Dose Levels. | Author: Battelle | Year: 2001 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: ADME Study of 14C D5 in the Rat following a Single Nose-only Vapor Inhalation Exposure to 14C-D5 at Two Dose Levels. | Author: Battelle | Year: 2001 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In vivo Percutaneous Absorption of 14C-Decamethylcyclopentasiloxane in the Rat | Author: Dow Corning Corporation | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In vivo Percutaneous Absorption of 14C-Decamethylcyclopentasiloxane in the Rat | Author: Dow Corning Corporation | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition of 14C-Decmathylcyclopentasiloxane (D5) in Fisher 344 Rats when Delivered in Various Carriers Following the Administration of a Single Oral Dose. | Author: Dow Corning Corporation | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Disposition of 14C-Decmathylcyclopentasiloxane (D5) in Fisher 344 Rats when Delivered in Various Carriers Following the Administration of a Single Oral Dose. | Author: Dow Corning Corporation | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Absorption of Decamethylcyclopentasiloxane (D5) using the flow-through diffusion cell system for in vitro dermal absorption in human skin. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Absorption of Decamethylcyclopentasiloxane (D5) using the flow-through diffusion cell system for in vitro dermal absorption in human skin. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In vitro absorption of decamethylcyclopentasiloxane (D5) in human skin: A comparison octamethylcyclotetrasiloxane (D4) | Author: McMahon JM Plotzke KP Jovanovic ML McNett DA Gallvan RH|Meek RG | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In vitro absorption of decamethylcyclopentasiloxane (D5) in human skin: A comparison octamethylcyclotetrasiloxane (D4) | Author: McMahon JM Plotzke KP Jovanovic ML McNett DA Gallvan RH|Meek RG | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In Vitro Percutaneous Absorption of 14C-D5 in Rat Skin. | Author: Dow Corning Corporation | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In Vitro Percutaneous Absorption of 14C-D5 in Rat Skin. | Author: Dow Corning Corporation | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Dermal absorption of 14C-decamethylcyclopentasiloxane (D5) in rats | Author: Plotzke KP McMahon JM Hubbell BG Meeks RG Mast RW | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Dermal absorption of 14C-decamethylcyclopentasiloxane (D5) in rats | Author: Plotzke KP McMahon JM Hubbell BG Meeks RG Mast RW | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In Vivo Percutaneous Absorption of 14C-D5 in Rat Skin. | Author: Dow Corning Corporation | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In Vivo Percutaneous Absorption of 14C-D5 in Rat Skin. | Author: Dow Corning Corporation | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Non-regulated study: Identification of metabolites of decamethylcyclopentasiloxane in fat collected from Fischer 344 rats following a single oral dose | Author: Dow Corning Corporation | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Non-regulated study: Identification of metabolites of decamethylcyclopentasiloxane in fat collected from Fischer 344 rats following a single oral dose | Author: Dow Corning Corporation | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Non-regulated study: Human Dermal Absorption of Decamethylcyclopentasiloxane (D5) | Author: University of Rochester Medical Center | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Non-regulated study: Human Dermal Absorption of Decamethylcyclopentasiloxane (D5) | Author: University of Rochester Medical Center | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Absorption Distribution and Excretion (ADE) study of 14C-decamethylcyclopentasiloxane (D5) in the female rat following a single nose-only vapour inhalation exposure to 14C-D5. | Author: Battelle | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Absorption Distribution and Excretion (ADE) study of 14C-decamethylcyclopentasiloxane (D5) in the female rat following a single nose-only vapour inhalation exposure to 14C-D5. | Author: Battelle | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Non-regulated study: Metabolites of decamethylcyclopentasiloxane (D5) in Rat Urine. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Non-regulated study: Metabolites of decamethylcyclopentasiloxane (D5) in Rat Urine. | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine | Author: Varaprath S. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine | Author: Varaprath S. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: A Study of Excretion of MESiO3/2 Moieties After Oral Administration of D5 | Author: Dow Corning Corporation | Year: 1988 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: A Study of Excretion of MESiO3/2 Moieties After Oral Administration of D5 | Author: Dow Corning Corporation | Year: 1988 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Monte Carlo analysis of tissue concentrations following occupational exposure to octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane using a physiologically based pharmacokinetic model. | Author: Clewell Andersen Tan and Yang | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Monte Carlo analysis of tissue concentrations following occupational exposure to octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane using a physiologically based pharmacokinetic model. | Author: Clewell Andersen Tan and Yang | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: A 28-day subchronic oral gavage feasibility study of various low molecular weight silicone oligomers in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: A 28-day subchronic oral gavage feasibility study of various low molecular weight silicone oligomers in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 14-day subchronic oral gavage study with decamethylcyclopentasiloxane in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 14-day subchronic oral gavage study with decamethylcyclopentasiloxane in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: One-Month Repeated Dose Inhalation Toxicity with decamethylcyclopentasiloxane in Rats. | Author: RCC Ltd | Year: 1995 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: One-Month Repeated Dose Inhalation Toxicity with decamethylcyclopentasiloxane in Rats. | Author: RCC Ltd | Year: 1995 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Effects of 4-week vapor inhalation of decamethylcyclopentasiloxane (D5) on Fischer 344 rats | Author: Kelly DW Neun DJ Thevenaz Ph Meeks RG and Mast RW | Year: 1995 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Effects of 4-week vapor inhalation of decamethylcyclopentasiloxane (D5) on Fischer 344 rats | Author: Kelly DW Neun DJ Thevenaz Ph Meeks RG and Mast RW | Year: 1995 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 28-Day Inhalation Toxicity and Splenic Antibody Formation Study of decamethylcyclopentasiloxane (D5) in Rats. | Author: WIL Research Laboratories Inc | Year: 1996 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 28-Day Inhalation Toxicity and Splenic Antibody Formation Study of decamethylcyclopentasiloxane (D5) in Rats. | Author: WIL Research Laboratories Inc | Year: 1996 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicology and Humoral Immunity Assessment of D5 following a 1-Month Whole Body Inhalation Exposure in Fischer 344 Rats. | Author: Burns-Naas L A et al. | Year: 1998 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Toxicology and Humoral Immunity Assessment of D5 following a 1-Month Whole Body Inhalation Exposure in Fischer 344 Rats. | Author: Burns-Naas L A et al. | Year: 1998 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicological and humoral immunity assessment in rats exposed for 28 days to decamethylcyclopentasiloxane (D5) vapor | Author: Burns LA Mast RW Naas DJ McCay JA and Klykken PC | Year: 1996 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Toxicological and humoral immunity assessment in rats exposed for 28 days to decamethylcyclopentasiloxane (D5) vapor | Author: Burns LA Mast RW Naas DJ McCay JA and Klykken PC | Year: 1996 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Non-regulated study: Effects of decamethylcyclopentasiloxane (D5) on cell proliferation in the liver of female Fischer 344 rats: a 28-day inhalation study. | Author: Dow Corning Corporation | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Non-regulated study: Effects of decamethylcyclopentasiloxane (D5) on cell proliferation in the liver of female Fischer 344 rats: a 28-day inhalation study. | Author: Dow Corning Corporation | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Sub-acute inhalation toxicity study of silicone oil KF 995 in rats. | Author: TNO | Year: 1984 | Guideline: 412 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Sub-acute inhalation toxicity study of silicone oil KF 995 in rats. | Author: TNO | Year: 1984 | Guideline: 412 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 28-day dermal study of decamethylcyclopentasiloxane (D5) in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 410 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 28-day dermal study of decamethylcyclopentasiloxane (D5) in rats. | Author: Dow Corning Corporation | Year: 1990 | Guideline: 410 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Twenty-one day repeated dermal in the rabbit of material SF-1202 | Author: Huntingdon Research Center | Year: 1979 | Guideline: 410 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: Twenty-one day repeated dermal in the rabbit of material SF-1202 | Author: Huntingdon Research Center | Year: 1979 | Guideline: 410 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Subakute toxikologische Untersuchungen|an Kanninchen. | Author: Bayer AG | Year: 1988 | Guideline: 410 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: Subakute toxikologische Untersuchungen|an Kanninchen. | Author: Bayer AG | Year: 1988 | Guideline: 410 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: 28-Day percutaneous Toxicity study | Author: Muller D | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: 28-Day percutaneous Toxicity study | Author: Muller D | Year: 1978 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: A Two-Generation Inhalation Reproductive Toxicity and Developmental Neurotoxicity Study of decamethylcyclopentasiloxane (D5) in Rats. | Author: WIL Research Laboratories Inc | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: A Two-Generation Inhalation Reproductive Toxicity and Developmental Neurotoxicity Study of decamethylcyclopentasiloxane (D5) in Rats. | Author: WIL Research Laboratories Inc | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Evaluation of|decamethylcyclopentasiloxane (D5) in a 2-generation|inhalation reproductive study in rats | Author: Stump DG. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Evaluation of|decamethylcyclopentasiloxane (D5) in a 2-generation|inhalation reproductive study in rats | Author: Stump DG. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: An Inhalation Range Finding Reproductive Toxicity Study of decamethylcyclopentasiloxane (D5) in the Rat. | Author: WIL Research Laboratories Inc | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: An Inhalation Range Finding Reproductive Toxicity Study of decamethylcyclopentasiloxane (D5) in the Rat. | Author: WIL Research Laboratories Inc | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Potential for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane to Interact With and Activate the Dopamine D2 Receptor in Rat Striatal Membranes | Author: University of Florida | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Potential for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane to Interact With and Activate the Dopamine D2 Receptor in Rat Striatal Membranes | Author: University of Florida | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: 14C-Decamethylcyclopentasiloxane (14C-D5): Bioconcentration in the Fathead Minnow (Pimephales promelas) Under Flow-Through Test Conditions. | Author: Dow Corning Corporation | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: 14C-Decamethylcyclopentasiloxane (14C-D5): Bioconcentration in the Fathead Minnow (Pimephales promelas) Under Flow-Through Test Conditions. | Author: Dow Corning Corporation | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Siliconflussigkeit NM 4005 Determination of the Acute Toxicity to Fish | Author: Huls Infracor | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Siliconflussigkeit NM 4005 Determination of the Acute Toxicity to Fish | Author: Huls Infracor | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Decamethylcyclopentasiloxane - Acute Toxicity to Daphnids (Daphnia magna) Under Flow-Through Conditions. | Author: Springborn Smithers | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Decamethylcyclopentasiloxane - Acute Toxicity to Daphnids (Daphnia magna) Under Flow-Through Conditions. | Author: Springborn Smithers | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Siliconflussigkeit NM 4005 Determination of the Acute Toxicity to Daphnia. Report . | Author: Huls | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Siliconflussigkeit NM 4005 Determination of the Acute Toxicity to Daphnia. Report . | Author: Huls | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: No information | Author: Bayer AG | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: No information | Author: Bayer AG | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Decamethylcyclopentasiloxane (D5) - Toxicity to the Freshwater Green Alga Pseudokirchneriella subcapitata | Author: Springborn Laboratories Inc. | Year: 2001 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Decamethylcyclopentasiloxane (D5) - Toxicity to the Freshwater Green Alga Pseudokirchneriella subcapitata | Author: Springborn Laboratories Inc. | Year: 2001 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Siliconeflussigkeit NM 4004 Growth Inhibition of the Green Algae Scenedesmus subspicatus 86.81.SAG | Author: Huls Infracor | Year: 1999 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Siliconeflussigkeit NM 4004 Growth Inhibition of the Green Algae Scenedesmus subspicatus 86.81.SAG | Author: Huls Infracor | Year: 1999 | Klimisch score: 4 (not assignable) | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Siliconflüssigkeit (Silicone liquid) NM 4005. Determination of Respiration Inhibition of Activated Sludge (88/302/EWG). | Author: Diefenbach R | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Siliconflüssigkeit (Silicone liquid) NM 4005. Determination of Respiration Inhibition of Activated Sludge (88/302/EWG). | Author: Diefenbach R | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis of Decamethylcyclopentasiloxane | Author: Dow Corning Corporation | Year: 2006 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis of Decamethylcyclopentasiloxane | Author: Dow Corning Corporation | Year: 2006 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Cyclopentasiloxane decamethyl- (D5) and Cyclotrisiloxane hexamethyl- (D3) - Determination of the Biodegradability of a Test Substance | Author: Gledhill W E . | Year: 2004 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Cyclopentasiloxane decamethyl- (D5) and Cyclotrisiloxane hexamethyl- (D3) - Determination of the Biodegradability of a Test Substance | Author: Gledhill W E . | Year: 2004 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Soil-Water Distribution of Decamethylcyclopentasiloxane (D5) Using a Batch Equilibrium Method | Author: Dow Corning Corporation | Year: 2007 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Soil-Water Distribution of Decamethylcyclopentasiloxane (D5) Using a Batch Equilibrium Method | Author: Dow Corning Corporation | Year: 2007 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Simultaneous Determination of Partition Coefficients for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane. | Author: Xu S Kropscott B | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Simultaneous Determination of Partition Coefficients for Octamethylcyclotetrasiloxane and Decamethylcyclopentasiloxane. | Author: Xu S Kropscott B | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (D5) by the Slow-Stirring Method Using Gas Chromogratography and Mass Spectrometry. | Author: Kozerski G E Shawl H R | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (D5) by the Slow-Stirring Method Using Gas Chromogratography and Mass Spectrometry. | Author: Kozerski G E Shawl H R | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the 1-Octanol/Water Partition Coefficient of Decamethylcyclopentasiloxane (d5) by the Slow-Stirring Method Using Gas Chromatography and Mass Spectrometry | Author: Dow Corning Corporation | Year: 2007 | Guideline: 123 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |