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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Characterization of "EP306 /Acid Water" before Start of Toxicological and Ecological Studies | Author: BASF AG, GKA/C - E 210 | Year: 2007 | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Characterization of "EP306 /Acid Water" before Start of Toxicological and Ecological Studies | Author: BASF AG, GKA/C - E 210 | Year: 2007 | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physico-chemical Properties of "Dicarbonsaeure-Loesung DCPF aus B770 Prst. 77 deperoxidiert v. 15.1.2008" | Author: BASF SE | Year: 2008 | Guideline: 102 | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Physico-chemical Properties of "Dicarbonsaeure-Loesung DCPF aus B770 Prst. 77 deperoxidiert v. 15.1.2008" | Author: BASF SE | Year: 2008 | Guideline: 102 | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: BASF AG, ZSA/P - M 325 | Year: 1991 | Guideline: 103 | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: No information | Author: BASF AG, ZSA/P - M 325 | Year: 1991 | Guideline: 103 | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Year: 2009 | Guideline: 103 | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physico-chemical Properties of "Dicarbonsaeure-Loesung DCPF aus B770 Prst. 77 deperoxidiert v. 15.1.2008" | Author: BASF SE | Year: 2008 | Guideline: 109 | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physico-chemical Properties of "Dicarbonsaeure-Loesung DCPF aus B770 Prst. 77 deperoxidiert v. 15.1.2008" | Author: BASF SE | Year: 2008 | Guideline: 109 | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Year: 2009 | Guideline: 104 | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: BASF AG, ZSA/P - M 325 | Year: 1991 | Guideline: 104 | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: No information | Author: BASF AG, ZSA/P - M 325 | Year: 1991 | Guideline: 104 | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: No information | Year: 2009 | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Octanol-water partition coefficient (Pow) of a solution of dicarbonsaeure | Author: BASF AG | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Octanol-water partition coefficient (Pow) of a solution of dicarbonsaeure | Author: BASF AG | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Octanol-Wasser-Verteilungskoeffizient POW einer wasserigen Natriumcarboxy latl6sung bei 25°C | Author: BASF AG | Year: 1989 | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Octanol-Wasser-Verteilungskoeffizient POW einer wasserigen Natriumcarboxy latl6sung bei 25°C | Author: BASF AG | Year: 1989 | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Wasserlösichkeit NAC-Lösung, QM-statement | Author: BASF SE, D-67056 Ludwigshafen | Year: 2009 | Guideline: 105 | GLP: N. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Wasserlösichkeit NAC-Lösung, QM-statement | Author: BASF SE, D-67056 Ludwigshafen | Year: 2009 | Guideline: 105 | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Year: 2009 | Guideline: 105 | GLP: N. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Oberflächenspannung Sauerwasser (Dicarbonsäurelösung) | Author: BASF AG | Year: 1988 | Guideline: 115 | GLP: N. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Oberflächenspannung Sauerwasser (Dicarbonsäurelösung) | Author: BASF AG | Year: 1988 | Guideline: 115 | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Bestimmung des Flammpunkts nach DIN 51758 | Author: BASF AG | Year: 1990 | Guideline: A.9 | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Bestimmung des Flammpunkts nach DIN 51758 | Author: BASF AG | Year: 1990 | Guideline: A.9 | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Sicherheitstechnische Kenndaten Dicarbonsäurelösung (Abstreifsäure) | Author: BASF AG | Year: 1987 | Guideline: A.9 | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Sicherheitstechnische Kenndaten Dicarbonsäurelösung (Abstreifsäure) | Author: BASF AG | Year: 1987 | Guideline: A.9 | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Sicherheitstechnische Kenndaten Dicarbonsäurelösung | Author: BASF AG | Year: 1987 | Guideline: A.15-16 | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Sicherheitstechnische Kenndaten Dicarbonsäurelösung | Author: BASF AG | Year: 1987 | Guideline: A.15-16 | GLP: N. | - |
| Phys-Chem | Storage stability and reactivity towards container material | Robust Study Summary -- Title: Bewertung der Korrosivität von Dicarbonsäurelösung aus Antwerpen | Author: BASF SE | Year: 2011 | GLP: N. | - |
| Phys-Chem | Storage stability and reactivity towards container material | Right to refer to study -- Title: Bewertung der Korrosivität von Dicarbonsäurelösung aus Antwerpen | Author: BASF SE | Year: 2011 | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: COP Acid composition with pKa values | Author: Noorduin A.J. | Year: 2017 | Guideline: 112 | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Title: COP Acid composition with pKa values | Author: Noorduin A.J. | Year: 2017 | Guideline: 112 | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Bestimmung der kinematischen Viskosität | Author: BASF AG | Year: 1990 | Guideline: 114 | GLP: N. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Bestimmung der kinematischen Viskosität | Author: BASF AG | Year: 1990 | Guideline: 114 | GLP: N. | - |
| Environmental | Phototransformation in air | Robust Study Summary -- Title: No information | Author: unknown | Year: 2009 | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of the Biodegradability of Dicarbonic acid solution in the CO2-Evolution Test | Author: BASF AG | Year: 1997 | Guideline: 301B | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of the Biodegradability of Dicarbonic acid solution in the CO2-Evolution Test | Author: BASF AG | Year: 1997 | Guideline: 301B | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: No information | Author: unknown | Year: 2009 | GLP: N. | - |
| Environmental | Phototransformation in water | Robust Study Summary -- Title: Data assessment | Author: BASF SE | Year: 2009 | GLP: N. | - |
| Environmental | Phototransformation in soil | Robust Study Summary -- Title: No information | Author: unknown | Year: 2009 | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Report on the study of the acute toxicity of dicarbonic acid solution on the Golden orfe (Leuciscus idus L., golden variety | Author: BASF AG | Year: 1987 | Guideline: 203 | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Report on the study of the acute toxicity of dicarbonic acid solution on the Golden orfe (Leuciscus idus L., golden variety | Author: BASF AG | Year: 1987 | Guideline: 203 | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Determination of the acute effect of Dicarboxylic acid solution on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF AG | Year: 1997 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Determination of the acute effect of Dicarboxylic acid solution on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF AG | Year: 1997 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Determination of the acute effect of Dicarboxylic acid solution on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF AG | Year: 1997 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Determination of the acute effect of Dicarboxylic acid solution on the swimming ability of the water flea Daphnia magna STRAUS | Author: BASF AG | Year: 1997 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: EP 306 /Acid Water Determination of the inhibitory effect on the cell multiplication of unicellular green algae Desmodesmus subspicatus CHODAT | Author: BASF AG | Year: 2007 | Guideline: 201 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: EP 306 /Acid Water Determination of the inhibitory effect on the cell multiplication of unicellular green algae Desmodesmus subspicatus CHODAT | Author: BASF AG | Year: 2007 | Guideline: 201 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Bacterial growth inhibition test according Bringmann-Kuehn | Author: BASF AG | Year: 1987 | Guideline: 209 | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Bacterial growth inhibition test according Bringmann-Kuehn | Author: BASF AG | Year: 1987 | Guideline: 209 | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Die Bernsteinsaeureausscheidung bei Stoffwechselbelastung mit hoeheren n-Dicarbonsaeuren. | Author: Weitzel G. | Year: 1947 | Guideline: 417 | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Stoffwechselversuche mit Adipinsaeure. | Author: Weitzel G. | Year: 1942 | Guideline: 417 | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The decomposition of muconic and adipic acids in the animal body. | Author: Mori Y. | Year: 1918 | Guideline: 417 | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Vertraeglichkeit und Ausscheidungsverhaeltnisse von Dicarbonsaeuren. | Author: Enders A. | Year: 1941 | Guideline: 417 | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Vertraeglichkeit und Ausscheidungsverhaeltnisse von Dicarbonsaeuren. | Author: Enders A. | Year: 1941 | Guideline: 417 | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Intermediary metabolism of adipic acid. | Author: Rusoff I.I. et al. | Year: 1960 | Guideline: 417 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Stoffwechselversuche mit Dicarbonsaeuren. | Author: Bernhard K., Andreae M. | Year: 1937 | Guideline: 417 | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Report on the study of acute oral toxicity | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 423 | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report on the study of acute oral toxicity | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 423 | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Bericht ueber die Pruefung der akuten oralen Toxizitaet von Adipinsaeure an der Ratte | Author: BASF AG | Year: 1978 | Guideline: 423 | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Bericht ueber die gewerbetoxikologische Vorpruefung | Author: BASF AG | Year: 1978 | Guideline: 423 | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Safety of adipic acid as compared with citric and tartaric acid. | Author: Horn H.J., Holland E.G., Hazleton L.W. | Year: 1957 | Guideline: 423 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Mutagenic Evaluation of Compound FDA 71-50, Adipic Acid, December 9, 1974. | Author: Litton Bionetics, Inc. | Year: 1974 | Guideline: 423 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral Toxicity | Author: Solutia | Year: 1975 | Guideline: 423 | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Akute Inhalationstoxizitaet LC50 an der Ratte, Staub-Aerosol-Versuch | Author: BASF AG | Year: 1981 | Guideline: 403 | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: No information | Author: Solutia Inc. | Year: 1975 | Guideline: 402 | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Test for acute irritation/corrosion on the intact skin of white rabbits based to OECD. | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 404 | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Test for acute irritation/corrosion on the intact skin of white rabbits based to OECD. | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 404 | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Skin Irritation Test on Rabbits | Author: Haskell Laboratory for Toxicology and Industrial Medicine | Year: 1974 | Guideline: 404 | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Skin Irritation Test on Rabbits | Author: Haskell Laboratory for Toxicology and Industrial Medicine | Year: 1974 | Guideline: 404 | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Bericht ueber die Pruefung der akuten Haut- und Schleimhautreizwirkung von Adipinsaeure am Kaninchen, | Author: BASF AG | Year: 1978 | Guideline: 404 | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute Skin Irritation | Author: Solutia | Year: 1975 | Guideline: 404 | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Bericht ueber die Pruefung der primaeren Hautreizwirkung von Adipinsaeure an der Rueckenhaut weisser Kaninchen | Author: BASF AG | Year: 1978 | Guideline: 404 | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Report on the acute irritation to the eye of the White Rabbit based on OECD. | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 405 | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report on the acute irritation to the eye of the White Rabbit based on OECD. | Author: BASF AG, Department of Toxicology | Year: 1987 | Guideline: 405 | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: LPT Laboratory of Pharmacology and Toxicology KG | Author: LPT Laboratory | Year: 2004 | Guideline: 405 | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: LPT Laboratory of Pharmacology and Toxicology KG | Author: LPT Laboratory | Year: 2004 | Guideline: 405 | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Bericht ueber die Pruefung auf primaere Reizwirkung von Adipinsaeure am Auge weisser Kaninchen | Author: BASF AG | Year: 1978 | Guideline: 405 | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Bericht ueber die Pruefung auf primaere Reizwirkung von Adipinsaeure am Auge weisser Kaninchen | Author: BASF AG | Year: 1978 | Guideline: 405 | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Dicarbonsaeure Loesung peroxidfrei EP306/Acid Water: Murine Local Lymph Node Assay (LLNA) | Author: BASF AG, Experimental Toxicology and Ecology | Year: 2010 | Guideline: B.6 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Dicarbonsaeure Loesung peroxidfrei EP306/Acid Water: Murine Local Lymph Node Assay (LLNA) | Author: BASF AG, Experimental Toxicology and Ecology | Year: 2010 | Guideline: B.6 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Primary Skin Irritation and Sensitization Tests on Guinea Pigs | Author: Haskell Laboratory for Toxicology and Industrial Medicine | Year: 1974. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Primary Skin Irritation and Sensitization Tests on Guinea Pigs | Author: Haskell Laboratory for Toxicology and Industrial Medicine | Year: 1974. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Diacides AGS Écailles: Skin sensitization test in guinea pigs (Maximization method) | Author: Pelcot C. | Year: 2004 | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Diacides AGS Écailles: Skin sensitization test in guinea pigs (Maximization method) | Author: Pelcot C. | Year: 2004 | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Safety of adipic acid as compared with citric and tartaric acid. | Author: Horn H.J., Holland E.G., Hazleton L.W. | Year: 1957 | Guideline: 407 | Adequacy: key study | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Ueber den Stoffwechsel und die Vertraeglichkeit der Adipinsaeure. | Author: Lang K., Bartsch A-R. | Year: 1953 | Guideline: 407 | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds. | Author: Moody D.E., Reddy J.K. | Year: 1978 | Guideline: 407 | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Ueber den Stoffwechsel und die Vertraeglichkeit der Adipinsaeure. | Author: Lang K., Bartsch A-R . | Year: 1953 | Guideline: 407 | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Clinical and experimental characteristics of the toxic action of adipic acid and bases for setting its TLV in workplace air. | Author: Krapotkina M.A. et al. | Year: 1981 | Guideline: 412. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The subacute inhalation toxicity of 109 industrial chemicals. | Author: Gage J.C. | Year: 1970 | Guideline: 412 | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella typhimurium/Escherichia coli Reverse Mutation Assay (Standard Plate Test and Preincubation Test) with Dicarboxylic acid solution. | Author: BASF AG, Department of Toxicology | Year: 1998 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella typhimurium/Escherichia coli Reverse Mutation Assay (Standard Plate Test and Preincubation Test) with Dicarboxylic acid solution. | Author: BASF AG, Department of Toxicology | Year: 1998 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Study of Dicarboxylic acid solution in the Ames Salmonella/Mammalian-Microsome Mutagenicity Test and Escherichia coli/Mammalian-Microsome Reverse Mutation Assay (Standard Plate Test and Preincubation Test). | Author: BASF AG, Department of Toxicology | Year: 1998 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Study of Dicarboxylic acid solution in the Ames Salmonella/Mammalian-Microsome Mutagenicity Test and Escherichia coli/Mammalian-Microsome Reverse Mutation Assay (Standard Plate Test and Preincubation Test). | Author: BASF AG, Department of Toxicology | Year: 1998 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: In vitro Mammalian Cell Gene Mutation Test (HPRT-locus) in Chinese Hamster V79 Cells with Adipic Acid | Author: BSl Bioservice | Year: 2009 | Guideline: 476 | Adequacy: key study | GLP: Y. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: In vitro Mammalian Cell Gene Mutation Test (HPRT-locus) in Chinese Hamster V79 Cells with Adipic Acid | Author: BSl Bioservice | Year: 2009 | Guideline: 476 | Adequacy: key study | GLP: Y. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Mutagenic Evaluation of Compound FDA 71-50, Adipic Acid, | Author: Litton Bionetics, Inc. | Year: 1974 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Microbial mutagenesis testing of substances, | Author: Mortelmans K.E., Griffin A. | Year: 1982 | Guideline: 471. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial mutagenicity testing of 49 food ingredients gives very few positive results. | Author: Prival M.J., Simmon V.F., Mortelmans K.E. | Year: 1991 | Guideline: 471. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Microbial mutagenesis testing of Substances: compound report Adipic acid CAS 124-04-9 | Author: Simmon | Year: 1978 | Guideline: 471. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Mutagenic Evaluation of Compound FDA 71-50, Adipic Acid | Author: Litton Bionetics, Inc. | Year: 1974 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: The results of microbial mutation test for forty-three industrial chemicals. | Author: Shimizu H. et al. | Year: 1985 | Guideline: 471. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: EP306/Acid Water: Cytogenetic Study in-vivo in the Mouse Micronucleus Test (Two oral adminsitration). | Author: BASF AG, Department of Experimental Toxicology and Ecology | Year: 2007 | Guideline: 483 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: EP306/Acid Water: Cytogenetic Study in-vivo in the Mouse Micronucleus Test (Two oral adminsitration). | Author: BASF AG, Department of Experimental Toxicology and Ecology | Year: 2007 | Guideline: 483 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Mutagenic Evaluation of Compound FDA 71-50, Adipic Acid, | Author: Litton Bionetics, Inc. | Year: 1974 | Guideline: 483 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Mutagenic Evaluation of Compound FDA 71-50, Adipic Acid, | Author: Litton Bionetics, Inc. | Year: 1974 | Guideline: 483 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Carcinogenicity | Robust Study Summary -- Title: Safety of adipic acid as compared with citric and tartaric acid. | Author: Horn H.J., Holland E.G., Hazleton L.W. | Year: 1957 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Toxicity to reproduction: other studies | Robust Study Summary -- Title: Safety of adipic acid as compared with citric and tartaric acid. | Author: Horn H.J., Holland E.G., Hazleton L.W. | Year: 1957 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic Evaluation of FDA 71-50 (Adipic Acid) in Rabbits, | Author: Food and Drug Res Labs, Inc. | Year: 1974 | Guideline: 414 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic Evaluation of FDA-71-50 (Adipic Acid) in mice, February 26, 1973. | Author: Food and Drug Res Labs, Inc. | Year: 1972 | Guideline: 414 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic Evaluation of FDA-71-50 (Adipic Acid) Report No. FDABF-GRAS 069, PB-221802, pp 1-42, February 26, 1972. | Author: Food and Drug Res Labs, Inc. | Year: 1972 | Guideline: 414 | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Specific investigations: other studies | Robust Study Summary -- Title: Toxicity and biodegradation of products from polyester hydrolysis | Author: Kim M-N. et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | Specific investigations: other studies | Robust Study Summary -- Title: Inhibitory effects of lipophilic acids and related compounds on bacteria and mammalian cells. | Author: Sheu C.W. et al. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Health Hazard Evaluation Report No HETA-83-166-1594, A, . | Author: Cummings C.E., Roseman J. | Year: 1985 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 18 | Author: OECD SIDS | Year: 2004 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Clinical and experimental characteristics of the toxic action of adipic acid and bases for setting its TLV in workplace air. | Author: Krapotkina M.A. et al. | Year: 1981 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Adipic acid | Author: American Conference of Governmental Industrial Hygienists (ACGIH) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Benign adipic aciduria. | Author: Hunnemann D.E., Wilichowski E., Hanefeld F. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Origins of spurious organic acidurias | Author: Joseph F., Russo T.M. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Occupational medical experiences with Adipic acid as well as glutaric acid and succinic acid | Author: Leng G. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 124-04-9 | EC 204-673-3 | Adipic Acid) |
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| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Evaluation of Certain Food Additives | Author: Joint FAO/WHO Expert Commitee on Food Additives (JECFA) | Year: 1978 | Klimisch score: 4 - Not assignable. | - |
| Toxicological | Additional toxicological information | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 18 | Author: OECD/SIDS | Year: 2004. | - |