You are here: Home> Turkey>TR-REACH>CAS 75-09-2> CAS 75-09-2 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: CRC handbook of chemistry and physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of chemistry and physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC handbook of chemistry and physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Weast R.C. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC handbook of chemistry and physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Verschueren K. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Horvath A.L. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation of log Kow for dichloromethane (CAS 75â€09â€2 ) using EPISUITE 4.0 | Author: Zvinavashe E. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Estimation of log Kow for dichloromethane (CAS 75â€09â€2 ) using EPISUITE 4.0 | Author: Zvinavashe E. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: No author provided | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Schwer entzuendbare Gase und Daempfe - Erweiterung der europaeischen Norm EN 1839 | Author: Brandes W., Milde J., Schroeder V. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: No information | Author: Nabert K., Schön G. | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: No information | Author: Steen H. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Schwer entzuendbare Gase und Daempfe - Erweiterung der europaeischen Norm EN 1839 | Author: Brandes W., Milde J., Schroeder V. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: No information | Author: Sax N.I., Lewis R.J. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Sicherheitstechnische Kennzahlen brennbarer Gase und Dämpfe | Author: Nabert K., Schön G. | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Explosionsgefahren beim Umgang mit Chlorkohlenwasserstoffen und deren Gemischen mit brennbaren Flüssigkeiten | Author: Steen H., Redeker T. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Explosionsgefahren beim Umgang mit Chlorkohlenwasserstoffen und deren Gemischen mit brennbaren Flüssigkeiten | Author: Steen H., Redeker T. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Author: Nabert K., Schön G. | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: Steen H., Redeker T. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: Steen H., Redeker T. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane trichloroethylene tetrachloroethylene and 111-trichloroethane | Author: Beek van L. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane trichloroethylene tetrachloroethylene and 111-trichloroethane | Author: Beek van L. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Ophthalmic toxicology of dichloromethane | Author: Ballantyne B. et al. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of contact hypersensitivity to Dichloromethane in the mouse (Local Lymph Node Assay) | Author: Huygevoort AHBM | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Assessment of contact hypersensitivity to Dichloromethane in the mouse (Local Lymph Node Assay) | Author: Huygevoort AHBM | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity of cosmetic ingredients licensed by the European Communities | Author: Gocke E. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: The MAK Collection for Occupational Health and Safety - Dichloromethane | Author: MAK | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Dichloromethane | Author: IARC | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Methylene Chloride (Second Edition) | Author: WHO | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity study with dichloromethane in rats. | Author: Janssen P.J.M., Pot T.E. | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity study with dichloromethane in rats. | Author: Janssen P.J.M., Pot T.E. | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Toxicity of methylene chloride to daphnids | Author: McCarty W.M. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Toxicity of methylene chloride to daphnids | Author: McCarty W.M. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Toxicity of Cadmium Copper Zinc Ammonia 33'-Dichlorobenzidine 26-Dichloro-4-Nitroaniline Methylene Chloride and 246- Trichlorophenol to Juvenile Grass Shrimp and Kilifish | Author: Burton D.T., Fisher D.J. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Effects of Bacterial Host and Dichloromethane Dehalogenase on the competitiveness of Methylotrophic Bacteria Growing with Dichloromethane | Author: Gisi D. et al. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Molecular characterization of dichloromethane-degrading Hyphomicrobium strains using 16 S rDNA and DCM dehalogenase gene sequences | Author: Nikolausz M. et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Isolation of a Xanthobacter sp. degrading dichloromethane and characterization of the gene involved in the degradation | Author: Emanuelsson MAE et al. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Metabolism of dichloromethane by the strict anaerobe dehalobacterium formicoaceticum | Author: Magli A., Messmer M., Leisinger T. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: A novel dichloromethane-degrading Lysinibacillus sphaericus strain wh22 and its degrative plasmid | Author: Wu S.J. et al. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: A mathematical model of biodegradability screening tests as an aid to interpretation of observed results | Author: Painter H.A., King E.F. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dichloromethane utilized by an anaerobic mixed culture: acetogenesis and methanogenesis | Author: Stromeyer S.A. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Bacterial Degradation of Dichloromethane | Author: Brunner W., Staub D., Leisinger T. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biological treatability of specific organic compounds found in chemical industry wastewaters | Author: Stover E.L., Kincannon D.F. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Specialized bacterial strains for the removal of dichloromethane from industrial waste | Author: Galli R., Leisinger T. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dichloromethane dehalogenase with improved catalytic activity isolated from a fast-growing dichloromehtane-utilizing bacterium | Author: Scholtz R. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: The biodegradation of methylene chloride in soils | Author: Davis J.W., Madsen S.S. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methylene Chloride - Second Edition | Author: WHO | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Basic mirobial degradation rates and chemical byproducts of selected organic compounds | Author: Davis E.M. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dehalogenation of Dichloromethane by Cell Extracts of Hyphomicrobium DM2 | Author: Stucki G. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Microbes enzymes and genes involved in dichloromethane utilization | Author: Leisinger T. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradability of dichloromethane (CAS 75-09-2) in the closed bottle test (OECD TG 301D) | Author: Ginkel van C.G. | Year: 2012 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradability of dichloromethane (CAS 75-09-2) in the closed bottle test (OECD TG 301D) | Author: Ginkel van C.G. | Year: 2012 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Genetic Adaptation of Bacteria to Halogenated Aliphatic Compounds | Author: Janssen D.B., Ploeg van der J.R., Pries F. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Protein engineering studies of dichloromethane dehalogenase/glutathione S-transferase from Methylophilus sp strain DM11 Ser 12 but not Tyr6 is required for enzym activity | Author: Vuilleumier S., Leisinger T. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of dichloromethane in an estuarine environment | Author: Krausova V.I., Robb F.T., Gonzalez J.M. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of dichloromethane and its utilization as a growth substrate under methanogenic conditions | Author: Freedman D.L., Gossett J.M. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Dichloromethane as the sole carbon source for an acetogenic mixed culture and isolation of a fermentative dichloromethane-degrading bacterium | Author: Braus-Stromeyer S.A. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Dichloromethane | Author: OECD SIDS | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Health assessment document for dichloromethane (methylene chloride). Final report | Author: Bayard S.P. et al. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Assessment of ready biodegradability of dichloromethane using weight of evidence approach | Author: Meussen B., Ginkel van C.G. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Right to refer to study -- Title: Assessment of ready biodegradability of dichloromethane using weight of evidence approach | Author: Meussen B., Ginkel van C.G. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |