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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: The Condensed Chemical Dictionary (10th Ed) | Author: Hawley G | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of the Water Solubility of 4-methylpentan-2-ol | Author: Mollandin G & Herrmann S | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of the Water Solubility of 4-methylpentan-2-ol | Author: Mollandin G & Herrmann S | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: I-Lab Service: ACD/LogP v8.02 for MIBC | Author: ACD Inc. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: METHYL ISOBUTYL CARBINOL SKIN IRRITATION TO THE RABBIT | Author: Parcell BI | Year: 1998 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: METHYL ISOBUTYL CARBINOL SKIN IRRITATION TO THE RABBIT | Author: Parcell BI | Year: 1998 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: METHYL ISOBUTYL CARBINOL EYE IRRITATION TO THE RABBIT | Author: Parcell BI | Year: 1998 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: METHYL ISOBUTYL CARBINOL EYE IRRITATION TO THE RABBIT | Author: Parcell BI | Year: 1998 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: SKIN SENSITIZATION TEST IN GUINEA-PIGS (Maximization method of Magnusson B. and Kligman A.M.) | Author: de Jouffrey S | Year: 1997 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: SKIN SENSITIZATION TEST IN GUINEA-PIGS (Maximization method of Magnusson B. and Kligman A.M.) | Author: de Jouffrey S | Year: 1997 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: The Results of Microbial Mutation Test for Forty-Three Industrial Chemicals | Author: Shimizu H et al. | Year: 1985 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Methyl isobutylcarbinol - In vitro mammalian cell gene mutation test in L5178Y TK+/- mouse lymphoma cells | Author: Sire G | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Methyl isobutylcarbinol - In vitro mammalian cell gene mutation test in L5178Y TK+/- mouse lymphoma cells | Author: Sire G | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: RANGE-FINDING TOXICITY DATA: LIST IV | Author: Smyth HF Carpenter CP & Weil CS | Year: 1951 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: SPECIAL REPORT on The Acute Toxicity of Methyl Amyl Alcohol | Author: Carpenter CP | Year: 1948 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: RANGE-FINDING TOXICITY DATA: LIST IV | Author: Smyth HF Carpenter CP & Weil CS | Year: 1951 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: SPECIAL REPORT on The Acute Toxicity of Methyl Amyl Alcohol | Author: Carpenter CP | Year: 1948 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Comparative metabolism of methyl isobutyl carbinol and methyl isobutyl ketone in male rats | Author: Gingell R et al. | Year: 2003 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Final Report Combined Repeated Dose Toxicity and Reproduction/Developmental Toxicity Study of Diacetone Alcohol on Rats | Author: MHW | Year: 1997 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 123-42-2 | EC 204-626-7 | 4-hydroxy-4-methylpentan-2-one) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: TOXICOLOGY AND CARCINOGENESIS STUDIES OF METHYL ISOBUTYL KETONE (CAS NO. 108-10-1) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) | Author: NTP | Year: 2007 | Guideline: 451 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 108-10-1 | EC 203-550-1 | 4-methylpentan-2-one) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: TOXICOLOGY AND CARCINOGENESIS STUDIES OF METHYL ISOBUTYL KETONE (CAS NO. 108-10-1) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) | Author: NTP | Year: 2007 | Guideline: 451 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 108-10-1 | EC 203-550-1 | 4-methylpentan-2-one) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure | Author: Stout MD et al. | Year: 2008 | Guideline: 451 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 108-10-1 | EC 203-550-1 | 4-methylpentan-2-one) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure | Author: Stout MD et al. | Year: 2008 | Guideline: 451 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 108-10-1 | EC 203-550-1 | 4-methylpentan-2-one) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Final Report Combined Repeated Dose Toxicity and Reproduction/Developmental Toxicity Study of Diacetone Alcohol on Rats | Author: MHW | Year: 1997 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 123-42-2 | EC 204-626-7 | 4-hydroxy-4-methylpentan-2-one) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Methyl Isobutyl Carbinol Acute Toxicity to Fish | Author: Daly EC | Year: 1999 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Methyl Isobutyl Carbinol Acute Toxicity to Fish | Author: Daly EC | Year: 1999 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: 4-Methylpentan-2-ol: An Acute Toxicity Study with the Daphnid Daphnia, magna STRAUS | Author: Marino TA et al. | Year: 2003 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: 4-Methylpentan-2-ol: An Acute Toxicity Study with the Daphnid Daphnia, magna STRAUS | Author: Marino TA et al. | Year: 2003 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Methyl isobutyl carbinol activated sludge-respiration inhibition test | Author: Barnes S | Year: 1998 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Methyl isobutyl carbinol activated sludge-respiration inhibition test | Author: Barnes S | Year: 1998 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methyl isobutyl carbinol: Assessment of Ready Biodegradability by Manometric Respirometry | Author: Burwood CE & Dickinson RA | Year: 1998 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Methyl isobutyl carbinol: Assessment of Ready Biodegradability by Manometric Respirometry | Author: Burwood CE & Dickinson RA | Year: 1998 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Alcohol equation | Author: Guidance on information requirements and chemical safety assessment (IR & CSA) Chapter 16 "Environmental exposure estimate" | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |